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Bupropion is really an example of an antidepressant using an amphetamine-like structure just like ephedrine, and it can be an NDRI. Its motion bears extra resemblance to amphetamine than to fluoxetine in that its primary manner of therapeutic motion includes norepinephrine and also to a lesser degree dopamine, but In addition, it releases some serotonin from presynaptic clefts. It should not be made use of with ephedrine, as it may raise the probability of Unwanted effects.

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